Roles and Responsibilities of the NIH Liaisons to PhenX Steering Committee
In July 2013, a Genomic Resource Grant (U41) was awarded by the National Human Genome Research Institute to RTI International to:
- Enhance and update the PhenX Toolkit content;
- Implement new Toolkit capabilities and features;
- Map PhenX variables to completed studies in dbGaP;
- Continue and extend our collaborations.
The Genomic Resource Grant will build on the work that has been done to identify standard measures for the 21 research domains and the Substance Abuse and Addiction Collections of measures. First assembled in 2007, the PhenX Steering Committee (SC) has been re-established to support and guide this consensus based process that identifies standard measures for collaborative research.
Liaisons from the National Institutes of Health (NIH) Institutes and Centers (IC) will continue to be key stakeholders in the PhenX Toolkit. IC liaisons are invited to participate in SC and Working Group (WG) meetings, may serve as WG members, and help disseminate information about the PhenX Toolkit to the research community.
WGs composed of six to eight scientists with relevant expertise will be established for each of four new domains. Each WG will have a chair or co-chairs, include a liaison from the SC, and will be supported by an RTI WG manager and supervisor. It is anticipated that each ERP will address four domains in FY 2014, six in FY 2015; six in FY 2016 and five in FY 2017. The task of the WG is to identify up to 15 measures for each domain. Each WG will use a consensus process to deliver a set of high-priority measures for inclusion in the PhenX Toolkit.
Expert Review Panels (ERPs) composed of up to three scientists with relevant expertise will also be established to review existing domain-specific content in the Toolkit. Each ERP will be supported by an RTI review panel manager and a domain expert. It is anticipated that four ERPs will be assembled in FY 2014; six in FY 2015; six in FY 2016 and five in FY 2017.
Roles of the Liaisons
- Attend in-person SC meetings in Washington DC and SC teleconferences as desired
- Communicate with IC colleagues and constituencies about PhenX
- Share information on relevant activities from their IC, grantees, and constituencies with the SC and RTI
- Identify information on relevant activities from their IC, grantees, and constituencies with the SC and RTI
- Communicate with the RTI team to ensure that the PhenX Toolkit meet the needs of their constituency
PhenX Senior Management Team
Carol M. Hamilton, Ph.D., Principal Investigator
Tabitha Hendershot, Co-Investigator
Deborah Maiese, M.P.A., Consensus Coordinator
Amanda Riley, PMP, Project Manager
Erin Ramos, Ph.D., M.P.H., Project Scientist
Teri Manolio, M.D., Ph.D., Director Division of Genomic Medicine
Information and materials about PhenX are posted at www.phenx.org or www.phenxtoolkit.org.